drvarun sqMedical 3D Printing & Bioprinting

Dr Varun Tyagi is a medical doctor who practices in India and writes about remarkable and historical landmarks throughout the medical world.  Dr Varun believes that 3D printing can help democratize medical care, making medical devices affordable and available to everyone on the planet.

Bonds Over The Bones: Student Joins Teacher To Fight Off Gap Of Bone Cancer

Bonds Over The Bones Student Joins Teacher To Fight Off Gap Of Bone Cancer

Linh Nam, a Harvard College Student was diagnosed with Osteosarcoma, a cancerous tumor in the bone when she was just ten years old and had a section of bone removed from her leg with a gap left and upcoming 10 surgeries over a decade. However, she joined with Hala Zreiqat, biomedical engineering professor, to work on a project that aims to create a biocompatible, artificial material with the same strength and porosity as real bone using 3D printing. Professor Zreigat’s team finally found a way to generate a porous core of a novel multi-component ceramic for bone implants using 3D printing which will be available to public around 2019.

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7-Year-Old Receives Surgery Planned Ahead Through 3D Printed Surgical Model

7 Year Old Receives Surgery Planned Ahead Through 3D Printed Surgical Model

7-year-old Isaiah Onassis Goberdhan, son of Barnaby Goberdhan had an aggressive tumor in his palate and nasal cavity and required surgery to remove it and approached Dr. Neha A. Patel, MD, Nortwell Pediatric Otolaryngologist at Cohen Children’s Medical Center. Working with Todd Goldstein, PhD, a Northwell Health Researcher, Dr. Patel create a personalized 3D rendering of Isaiah’s palate, using his CT and MRI scans and Formlabs technology was used to 3D print an anatomical model with the tumor, and one with it removed, in order to help the doctors and the family physically visualize the entire procedure ahead of time.

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Had Heart Attack? The New 3D Printed Cardiac Patch Heal The Permanent Damage

Had Heart Attack The New 3D Printed Cardiac Patch Heal The Permanent Damage

Once a person suffers myocardial infarction or heart attack in local language, some part of heart is destroyed permanently at cellular level which cannot recover or regenerate. However, scientists have developed 3D printed cardiac patches that can be used to repair hearts damaged by heart attacks, but only about five have been produced worldwide. A group of researchers 3D printed a world-first stretchable microfiber scaffold with a hexagonal design to which added specialized stem cells called iPS-Cardiomyocytes, which began to contract unstimulated on the scaffold. The work has been demonstrated on the actual hearts of pigs and being planned for human trials.

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Researchers Study Malaria Through Inexpensive 3D Printed Membrane Feeder

Researchers Study Malaria Through Inexpensive 3D Printed Membrane Feeder

A group of researchers from Imperial College, London is studying how malaria is transmitted, which requires mosquito test subjects to be infected with Plasmodium gametocytes – the blood stage parasites that actually cause malaria. In a Standard Membrane Feeding Assay (SMFA) test, an artificial membrane feeding apparatus, which simulates the host’s skin and body temperature, is used to get the mosquitoes to eat reconstituted blood containing the gametocytes. The researchers created the two-part membrane feeder design using the free, open source CAD modeling program Art of Illusion, then had Shapeways 3D print the parts out USP VI medical-grade “Fine Detail Plastic” acrylic resin (VisiJet M3 Crystal).

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Tokyo Researchers Reduce Production Costs For 3D Printed Medical Models

Tokyo Researchers Reduce Production Costs For 3D Printed Medical Models

A group of researchers from Tokyo Dental College set up a “One-stop 3D printing lab” at the college for the purposes of quickly and inexpensively designing and 3D printing models for oral and maxillofacial surgery. The researchers created their One-Stop 3D printing Lab by generalizing the software and hardware around its inexpensive Value3D MagiX MF-2000 desktop 3D printer from MUTOH Industries Ltd. The researchers determined, by 3D printing dental models daily, that the amount of preparation cost and modeling material can be lowered by increasing the laminating pitch.

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Youbionic Releases Redesigned Version Of Youbionic Arm

YouBionic Releases Redesigned Version Of Youbionic Arm

Italian Startup Youbionic was founded by Federico Ciccarese, and they have come up with a newer version of their Youbionic arm that is a Robotic Arm made of 3d printing and designed to perform all movements that a human Arm can accomplish. The arm is 3D printed out of PLA and uses Actuonix Linear Actuators. The company has rolled out the 3D Print Files of the arm for $149 and files for hand for $99 with hopes to fund his team’s further development.

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Treatment Of Cleft Lip And Palate Of Newborn Receives Aid From 3D Printing

Treatment Of Cleft Lip And Palate Of Newborn Receives Aid From 3D Printing

A study conducted at Technical University of Munich (TUM) described their virtual workflow, and also analyzed how effective semi-automated intraoral molding plate generation, or RapidNAM, is for helping to treat Cleft Lip and Palate (CLP). A 3D triangulation scanner from 3Shape in Denmark was used to digitalize the casts, and after creating a graphical user interface (GUI), an algorithm automatically detected the alveolar ridge, in order to find the monthly growth rate in the anatomical study of 32 healthy newborn babies. Special 3D software was used to help with plate expansions during the manual plate molding.

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Calcium Silicate Bone Scaffold By 3D Printing Shows Promise For Bone Grafts

Calcium Silicate Bone Scaffold By 3D Printing Shows Promise For Bone Grafts

A collaborative team of researchers from the National Taiwan University Hospital, the China Medical University Hospital, and Asia University have created a new bone substitute- Calcium Silicate Bone Scaffold that have both osteoconductive and osetoinductive potential to be used for bone grafts/repair required in people suffering from bone defects and disorders around the globe. The team explored the effects of various loading methods on novel grafting material bone morphogenetic protein-2 (BMP-2), which was loaded with a mesoporous calcium silicate (MesoCS) scaffold created with FDM 3D printing on a 3D bioprinter from GeSiM.

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Neuraxial Anesthesia Training Phantom Gets 3D Printed For Just 13$

Neuraxial Anesthesia Training Phantom Gets 3D Printed For Just 13

A group of researchers developed an inexpensive, 3D Printable Neuraxial Anesthesia Phantom through the use of free/libre/open-source (FLOS) software and data from CT scans to create a 3D model of the lumbar spine, which was then modified, put inside a digitally designed housing unit, and 3D printed out of PLA on a desktop system. The so 3d Printed Neuraxial Anesthesia Training Model cost only $13 and 25 hours of non-supervised 3D printing and two hours to assemble it, much less than creating a Simulab phantom.

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Russia Advances One Step Closer To Bioprinting Through Biocompatible 3D Polymeric Materials for Tissue Repair

Russia Advances One Step Closer To Bioprinting Through Biocompatible 3D Polymeric Materials for Tissue Repair

A team from the Polymer Materials for Tissue Engineering and Transplantology Laboratory of Peter the Great St. Petersburg Polytechnic University (SPbPU) in a joint project with researchers from the Russian Academy of Sciences and Pavlov First St. Petersburg State Medical University, has developed innovative, polymeric medical materials that can be used to fix human organs that have undergone trauma. The team have created a porous, 3D material made of chitosan – a bone tissue analog – and collagen which can mimic the body tissues and prevent itself from being rejected by the immunity of human body.

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Study Proves 3D Printed Splints Preferable Over Conventional Splints

Study Proves 3D Printed Splints Preferable Over Conventional Splints

A group of researchers compared conventional and digital additive manufacturing of hard occlusal stabilization splints (SS) using technical and clinical parameters and 14 subjects underwent sequence of tests and questionnaires for 12 weeks. On a scaled of great discomfort,  Conventional had a score of 42 while Additive Manufacturing performed 15, meaning 3D Printed Stabilization Splints are far more comfortable and preferred over the conventional ones.

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Artificial Lungs That You Can Carry In Bags

Artificial Lungs That You Can Carry In Bags

Biomedical engineer Dr. Joseph Potkay is working with high-resolution 3D Printing company Old World Labs on a research funded by the VA (Veteran Affairs), to create a prototype of the 3D printed artificial lung, which will be about a half-inch cube in size, hopefully able to fit in a backpack and be used for a week. It will be the first truly wearable artificial lung that’s compatible with living tissue and can provide both short- and long-term respiratory support, and microfluidic artificial lungs. The device has been tested in rabbits, with sheep testing planned for the future.

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India Achieves First Patient Specific Trauma Total Talus Replacement Through 3D Printing

India Achieves First Patient Specific Trauma Total Talus Replacement Through 3D Printing

Dr. Rajiv Shah, an Orthopedic Surgeon at Global Hospital along with 3D Printing Startup 3D Post in Vadodara, India, has successfully implanted a 3D printed implant in a trauma patient which was first of its kind since it was the first patient-specific 3D printed trauma implant through a total talus replacement. The implant was 3D Printed using EOS M 280 3D Printer using titanium as the implant material for a 32-year old man from Guajarat, India who suffered an accident that resulted in the loss of his talus bone.

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Porous Scaffolds From UPC Researchers For FDM 3D Printing Show Promises Fulfilled

Porous Scaffolds From UPC Researchers For FDM 3D Printing Show Promises Fulfilled

Researchers from the Polytechnic University of Catalonia (UPC) in Barcelona developed a new method of designing porous scaffolds for FDM 3D printing using a dual-extruder Sigma 3D printer from BCN3D to fabricate three sample scaffolds out of PLA, and then measuring their pore size and total porosity. They applied their model to a disc shape and defined three different variables: Distance between parallel planes; Number of base points for columns on each plane and Radius of each column.

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Man Gets Wolverine Like 3D Printed Titanium Metacarpal Implant

Man Gets Wolverine Like 3D Printed Titanium Metacarpal Implant

Paul D’Urso, MD, a neurosurgeon at Epworth Healthcare and the Executive Chairman of Australian medical device company Anatomics, together with Dr. Dan Rowe, engineers from the medical device company designed a 3D printed, patient-specific metacarpal implant to replace a patient’s two missing metacarpals and missing capitate that had resulted from his injury.  The implant was designed with titanium mesh and patient’s hand reconstruction surgery took place at Greenslopes Private Hospital in Queensland.

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Pakistani Researchers Create 3D Printed Drug Delivery Device

Pakistani Researchers Create 3D Printed Drug Delivery Device

Munam Arshad from Pakistan under his thesis for MS Mechanical Engineering, recently outlined the effectiveness of 3D Printing in drug delivery via a vibrating mechanism that moves the medications through small ‘slits.’ Using PMC-744 as the material of choice due to its biocompatibility and flexibility, the research team 3D Printed the final model using SOLIDWORKS and PLA, featuring one system with both a haptic motor and drug reservoir with drug release area .

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PLACTIVE 3D Printed Filament Is The New Focus Of NASA

PLACTIVE 3D Printed Filament Is The New Focus Of NASA

A Chilean startup Copper3D had recently unveiled PLACTIVE, an antibacterial 3D printing filament designed for the production of medical devices such as prosthetics and braces. Taking interest in PLACTIVE, the NASA Nebraska Space Grant is working with the University of Nebraska Omaha and Copper3D on a study of PLACTIVE and states the new material has already passed very exhaustive laboratory tests with +99.99% elimination of most dangerous bacterial strains.

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Germany Based Medical Company 3D Prints Hip Replacement Cup Cutters For Surgeons

Germany Based Medical Company 3D Prints Hip Replacement Cup Cutters For Surgeons

Endocon, a Germany-based medical device company and a GE Additive customer, has started 3D Printing a new device called Acetabular Cup Cutter for surgeons to remove hip replacement cups with cost-effectiveness and product reliability with better surgical experience. Using GE Additive’s Concept Laser Mlab Cusing 100R, which uses direct metal laser melting (DMLM) technology, Endocon 3D prints the blades for its endoCupcut in 17-4 PH stainless steel.

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Accessing Technology With Customizable 3D Printed Contactors

Accessing Technology With Customizable 3D Printed Contactors

Pole-Ergo, a group of French occupational therapists are working on a new project, an Adaptable Swtich or Contactor, which is a button that assists disabled people to have access over electronics. Through motor gestures without precision, it helps disabled people have way better access over computers, tablets, mobile phones or other devices. Using 3D Printing, Pole Ergo created a 3D Printed Contactor that can be modified according to the user’s motor characteristics, habits or tastes.

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TirboLox-L 3D Printed Lumabr Cage From Captiva Spine Receives FDA Clearance

Captiva Spine Receives FDA Clearance for 3D Printed Titanium Lumbar Cages

Florida-based Captiva Spine Inc., a privately owned medical device organization that was founded in 2007 has recently received 510(k) clearance from the FDA for its 3D Printed TirboLOX-L Titanium Lumbar Cages. TirboLOX-L Titanium Lumbar Cages uses 3D printing to form interbody fusion devices, made out of titanium alloy, with a double layer organic lattice structure and include the benefits such as the bone’s ability to successfully grow within its architecture, which can then help it achieve good kinematic properties.

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The Prodigal Hero Return: 3D Printing For Different Heroes

Cam Haight of Different Heroes Nonprofit Makes 3D Printed Prosthetic Hand for His Own Hero

The story of 5-year old Cameron Haight was undoubtedly inspiring, how he was born with Amniotic Band Syndrome (ABS) which cause his finger bones to fuse, skin webbing, indentations on one wrist and fingers and even amputations. With help from eNABLE and Robo R1+ 3D Printer, he started 3D Printing prosthetics for other children in need and now through Different Heroes, a non-profit organization raised by Cam and his parents, they were able to gift their favorite football team Carolina Panthers idol with an adult-sized version of his own 3D Printed Panthers Prosthetic Hand.

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Into The Future: Bionic Eye Is Nearly Ready

Breakthrough 3D Printed Bionic Eye Could Restore or Enhance Sight

A team of researchers at University of Minnesota researchers are working on what they call “Bionic Eye” by Custom 3D Printing photoreceptors on a hemispherical surface. The process consumed hemispherical glass dome, silver particle base ink, semiconducting polymer materials and approximately one hour. With 25% efficiency, they are now planning to create prototypes that are even more efficient and could be worked upon for implantation into a real eye, thereby restoring or improving sight.

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Aether and UCLA Collaborate Towards Developing 3D Printed Artificial Muscles

Aether and UCLA Collaborate Towards Developing 3D Printed Artificial Muscles

UCLA and Bioprinting Company Aether have collaborated to work towards 3D Printed Artificial Muscles by working together to develop technologies for faster, easier fabrication of soft artificial muscles and other multi-material structures. Aether will work on optimizing the Aether 1 bioprinter and its computer vision capabilities to automate the process of 3D printing soft robotic devices, improve print quality and ease of use and has also planned to launch software that will allow users to create 3D printable organs from medical images with the push of a button in around 2019.

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Snake Robot For Intraluminal Surgeries Gets Successfully 3D Printed

Snake Robot For Intraluminal Surgeries Gets Successfully 3D Printed

A group of researchers describe how they designed a novel multi-tool snake-like robot, called the i2 Snake (Intuitive Imaging Sensing Navigated and Kinematically Enhanced robot) for minimally invasive intraluminal surgery. They used a rolling-joint design, a bio-inspired mechanism that consists of two circular surfaces rolling against each other, however, standard rolling joints could slip, resulting in control inaccuracies or a dislocated joint. The researchers used an Mlab 3D printer from Concept Laser to manufacture a prototype of the optimized rolling joint which was then characterized in terms of precision and manipulation forces.

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Wound Dressings By 3D Printing Are The Future Of Healing

Wound Dressings By 3D Printing Are The Future Of Healing

Under a thesis by a student named Cristian Ghibaudo, 3D bioprinting was discussed regarding the better wound treatments under Onskin project based on microfibrillar cellulose, or MFC, and sustainable materials. The concept was developed in four modules: the moisturizing module (M1), the absorbent module (M2), the barrier module (M3) and the support module (M4). Using BioX 3D Printers, several wound dressing prototypes were 3D printed out of which the Flat prototype was selected concluding it had good mechanical properties and high resolution, plus it printed in only 30 minutes.

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Viability Check Of Organ Phantoms Made By 3D Printing

Viability Check Of Organ Phantoms Made By 3D Printing

A research team at American Association of Physicists in Medicine recently published an article revealing how effective 3D Printing is for producing Organ Phantoms (models of organs to test things like proper medication dosage). Three questions were explored including the resolution of 3D Printing, materials used against scanning modality and feasibility of radioactive solutions as per 3D Printing is concerned. 50 studies conducted later concluded that 3D Printing undoubtedly has some limits, but is the fastest growing and can be definitely considered the best approach for Organ Phantoms as the new materials are unveiled.

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War Victims Start Receiving 3D Printed Prosthetics

War Victims Start Receiving 3D Printed Prosthetics

Foundations like the Médecins Sans Frontières (MSF) Foundation and International Committee of the Red Cross (ICRC) are working round the clock to provide new life to more than 1 million victims of war in Syria, Iraq, Yemen and Jordan by providing them 3D Printed Prosthetics. Using the 3D Scanning Technology and 3D Printing simultaneously, the parts can be printed without even doctor-patient meeting, while also cut down the heavy cost of traditional prosthetics that tend to be unfit and uncomfortable to the wearer.

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3D Printing Helps Father Donate Kidney to Her Daughter End-Stage Kidney Disease

3D Printing Helps Father Donate Kidney to Her Daughter End Stage Kidney Disease

Pauline Fenton, a 22-year-old mother from Belfast was living with end-stage kidney disease, and was completely reliant on dialysis until her 45 year old father; William volunteered to donate one of his kidneys. William had a potentially cancerous cyst on the kidney he was going to donate which was successfully removed using axial3D printed model of his kidney, and the transplant took place successfully.

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Stratasys Continues to Help Veterans Through 3D Printed Orthotic Hands

Stratasys Continues to Help Veterans Through 3D Printed Orthotic Hands

3D printing solutions company Stratasys worked with the VA Center of Innovation (VACI) to install 3D printers in five VA hospitals across the country, helping veterans with custom 3D printed prosthetics and orthotics. Hand therapist Mary Matthews, with the help of Ben Salatin (Rehabilitation Engineer) made a 3D printed one piece orthotic for Newton, making it more comfortable and damage proof with increased aesthetics.

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Synthetic 3D Printed Ligaments To Be Available Soon For Surgeries

 Synthetic 3D Printed Ligaments To Be Available Soon For Surgeries

Dr. Christina Salas, PhD, a scientist at the University of New Mexico, is working on 3D Printed Ligaments which can allow for less-invasive surgery, and could be a more permanent solution as the synthetic 3D printed ligament would not wear out or weaken. Using the CT or MRI scan of patient’s damaged joint, an exact replica using 3D Bioprinting can be produced for replacement, and Dr. Salas has received a two-year, $150,000 grant for the research.

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Young Kid Receives Second Life With 3D Bioprinted Bladder

Young Kid Receives Second Life With 3D Bioprinted Bladder

Luke Massella was born with Spina Bifida, a medical condition that causes gap in spine, which required multiple surgeries to be able to walk. However, he faced bladder malfunction and kidney failure, for which Dr. Anthony Atala of Boston Children’s Hospital developed 3D Printed Bladder using Massella’s bladder tissue and modified 3D inkjet machines. The 14 hour surgery of transplantation of 3D Bioprinted Urinary Bladder was successful saving the now 27 year old Massella.

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regenHU & Wako Automation Assist 3D Bioprinting Along With Drug Discovery

regenHU Wako Automation Assist 3D Bioprinting Along With Drug Discovery

3D biotechnology company regenHU with Wako Automation combined to exploits the potential of cell-based therapies and 3D bioprinting to develop biomedical products for drug discovery and regenerative medicine. They will use their specialization of bioprinting solutions, laboratory automation and high content imaging for the same. They demonstrated their technologies at SLAS Conference in San Diego.

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Human Skin With Actual Pigmentation Gets 3d Printed

 Human Skin With Actual Pigmentation Gets 3d Printed

Researchers at A*STAR’s Singapore Institute of Manufacturing Technology (SIMTech) and the Singapore Centre for 3D Printing (SC3DP) at Nanyang Technological University have developed a way to create pigmentation in 3D printed skin by using bioprinting to control the distribution of melanin-producing skin cells, on a biomimetic tissue substrate. They used three different types of skin cells and drop on demand method of bioprinting to create the pigmented skin.

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Researchers Work Towards Building Medical Models for Peritoneal Cancer

Researchers Work Towards Building Medical Models for Peritoneal Cancer

Researchers at Ghent University have developed a 3D bioprinted model of a scaffold from PLA that more accurately replicates the size, porosity and mechanical and biochemical properties of peritoneal metastasis to treat Cancer. Cancerous cells are then cultivated for testing after which they implanted their model in the peritoneal cavities of a mice to test its working in vivo.

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FDA Clears 3D Printed Implants From Emerging Implant Tech

 FDA Clears 3D Printed Implants From Emerging Implant Tech

Emerging Implant Technologies (EIT), a German company, famous for its Cellular Titanium technology, has received FDA clearance again, to expand their EIT Cellular Titanium Cervical Cage to be used in multiple contiguous cervical levels (C2 to T1) and this is the first multi-level 3D printed cervical cage to enter the US market. It is designed to be used with autogenous and/or allogenic bone grafts to facilitate fusion, and should be used with supplemental fixation.

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Patients With High Risk of Atrial Fibrillation to Benefit From 3D Printed Occluder Device

 Patients With High Risk of Atrial Fibrillation to Benefit From 3D Printed Occluder Device

Researchers with Dalio Institute of Cardiovascular Imaging at New York are working to develop 3D printed, personalized soft LAA occluding devices that are customized to a specific patient’s anatomy. The team used CT images of a person’s heart and a CAD program to isolate the surface of the LAA with a 0.5 mm thick shell, adding a valve for inflation and mechanical stabilization to the design. The molds for occluder are then printed for casting and filling.

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KCE Report Addresses High Risk Medical Devices and Framework

 KCE Report Addresses High Risk Medical Devices and Framework

A report was published by the Belgian Health Care Knowledge Center (KCE), identifying 3 main types of 3D printed medical devices – Customizable, Standard and Custom-made. The report addresses risks and challenges of this technology and drafts an operational framework for these devices, over viewing their effectiveness, safety, cost, and legal issues.

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Digitalizing the Pharmaceuticals for 3D Printing

 Digitalizing the Pharmaceuticals for 3D Printing

Researchers from the University of Glasgow are using a chemical-to-digital converter to digitize the process of drug manufacturing to 3D print pharmaceuticals on demand. The digital code is used by the 3D printer to make a portable factory, which can make the drug by adding chemicals in a pre-defined, fail-safe sequence, making it possible for users to synthesize nearly any compound.

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Trachea Without Tissue Scaffolds: 3D Printing Advancements

 Trachea Without Tissue Scaffolds 3D Printing Advancements

Researchers from Nagasaki University in Japan are working on scaffold-free approaches for an artificial trachea by assessing the circumferential tracheal replacement using scaffold-free trachea-like grafts, generated from isolated cells in an inbred animal model. Regenova 3D bioprinter from Cyfuse Biomedical was used to assemble multicellular spheroids in a tube-shaped artificial trachea.

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Switzerland Advances in Mixing Laser Tech and 3D Printing for Tissue Repair

 Switzerland Advances in Mixing Laser Tech and 3D Printing for Tissue Repair

Researchers at EPFL in Switzerland have developed 3D printed microstructures with a 1.0 micron lateral and 21.5-micron axial printing resolution by detailing their approach towards existing laser-based microfabrication techniques which uses two-photon photopolymerization. The research team is now working toward clinical use for their technique while developing biocompatible photopolymers and a compact delivery system.

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