A Team of Researchers from UK experimented on using 3D Printing to create Orally disintegrating tablets (ODTs) of Ondansetron, a drug used in Vomiting receiving Chemotherapy, with the help of SLS 3D printing. The researchers developed a new type of ondansetron-cyclodextrin complexes meant to disintegrate rapidly, which were compared to Vonau Flash 8 mg, a commercial example of Ondansetron. Both 3D printed formulations disintegrated at ~15 s and released more than 90% of the drug within 5 min independent of the mannitol content, thus concluding that these results were comparable to those obtained with the commercial product with added benefit of using a manufacturing technology able to prepare medicines individualized to the patient.

Read More: https://www.mdpi.com/1999-4923/12/2/110