A group of Researchers in Italy approached 3D Printing to create Intraoral Occlusal Splints, which are used by dentists to treat temporomandibular disorders as they force muscles to relax and provide relief from pain. A 44-year-old man with unknown medical cause for pain in his jaws, was selected and fit with Intraoral Occlusal Splint to stop the pain and reposition the mandible. The team scanned the teeth of the patient and saved it as .stl file, followed by using 3D ProJet MJP 3600 Dental by 3D Systems to 3D print the Intraoral Splint, with VisiJetĀ® M3 Stoneplast acrylic resin, made for dental practices. The patient got relief of the pain within three weeks and has been advised to keep using the splint for another six months.