drvarun sqMedical 3D Printing & Bioprinting

Dr Varun Tyagi is a medical doctor who practices in India and writes about remarkable and historical landmarks throughout the medical world.  Dr Varun believes that 3D printing can help democratize medical care, making medical devices affordable and available to everyone on the planet.

Regenerating the Damaged Heart Tissues using 3D Printing

 Regenerate Heart

Mohammad Izadifar, a researcher at University of Saskatchewan (U of S) who also works with biomedical and chemical engineering, has been working on to combine engineering, 3D printing, and medicine to repair damaged hearts by regenerating heart muscle tissue. He is using a natural, algae-based hydrogel that’s biocompatible and won’t be rejected by the human body; the hydrogel is also biodegradable. The 3D Printed patch is theoretically believed to evolve into heart with regenerating blood vessels and tissues.


Source: https://news.usask.ca/articles/research/2017/combining-medicine-and-engineering-to-repair-a-damaged-heart.php

One Shot that delivers all Vaccines being developed by MIT Engineers

 One Shot Vaccine

Robert Langer and engineers at MIT have been researching on creating a single-dose biodegradable vaccine that can release the drugs or vaccines into the patient’s system on a specific schedule. Using Photolithography and 3D Printing, they have developed a microparticle that is made from a biocompatible, FDA-approved polymer and resembles a tiny cup. The fundamental idea is to assist babies in developing countries, who don’t always have access to doctors, could receive all the immunizations they needed for their first couple years of life in one shot.


Source: http://news.mit.edu/2017/one-vaccine-injection-could-carry-many-doses-0914

A Fix to 3D Printed Organs in Human Body by Prellis Biologics

 Prellis biologics

3D Printed Organs cannot survive in Human Body, unless they receive nutrients and oxygen from the body itself. Prellis, a company founded in 2016 has been working on the solution and 3D printing lymph node organoids are a perfect example of their work. The first 3D printed product to be developed will be Islets of langerhans, the insulin-producing part of the pancreas.


Source: http://www.businesswire.com/news/home/20170913005487/en/Human-Tissue-Engineering-Startup-Prellis-Biologics-Receives

3D Printed Utility Band by Havenlab provides Use for Intention feature for Amputees

 Utility band

A team at Havenlabs led by Mohammad Hasani, a mechanical engineering graduate from the City College of New York (CCNY), has finally unveiled their second product called the Utility Band for Upper Limb Amputees. Unlike prosthetic limbs, Utility band is made to be removed once the task is complete. The Utility Band was 3D Printed using LulzBot Mini 3D printer with Ninjaflex filament.


Source: https://www.3dmatters.com.au/news/havenlabs-releases-open-source-utility-band-to-help-amputees/

Aspect Biosystems partner with German Organizations to enhance 3D Printed Contractile Tissue

 Aspect Biosystems

The Canadian company, Aspect Biosystems is collaborating with German InSCREENeX and the Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM) to further develop 3D printed contractile tissue for pharmaceutical testing. The 3D BioRing Platform by Aspect Biosystems constitutes of 3D printed muscle tissue that contracts and relaxes like real muscle tissue. One of its use involves 3DBioRing Airway, which allows researchers to study bronchoconstriction and relaxation.


Source: https://www.aspectbiosystems.com/news/partners-inscreenex-fraunhofer-item

Europe receives the first 3D Printing Center by GE Healthcare

 ge healthcare 3d printing center

GE Healthcare, a part of GE company, has just opened a first European 3D printing and design center, located in Uppsala, Sweden, better known as the Innovative Design and Advanced Manufacturing Technology Center for Europe. Featuring both metal and polymer 3D printers as well as collaborative robots, teams of engineers will work together to design, test and produce 3D printed parts for GE Healthcare products and prepare them for manufacturing.


Source: http://www.genewsroom.com/press-releases/ge-healthcare-opens-its-first-european-3d-printing-and-design-center-284042

Medical Grade 3D Printing Filament by TreeD comes to market

 treed launches healthfil line

Italy-based filament producer TreeD Filaments has launched a new filament called the HealthFil, which is the first medical grade 3D printing filament line and can be used for multiple medical applications, ranging from busts and medical models to professional orthotics. The HealthFil filament is 100% certified for skin contact since it is compliant with the requirements of UNI EN 10993-5 European standard.


Source: https://3dadept.com/new-healthfil-filaments-from-treed-set-to-shake-up-medical-3d-printing/

Breast Prostheses produced for 1000 patients in need by Engineer

1000 3d print breast prostheses

Mechanical engineering technologist and social entrepreneur, Nneile Nkholise founded a company in the Free State town of Thaba Schu, South Africa in 2015, called the iMedTech Group, that uses 3D printing technology to manufacture breast prostheses. Using the resources and her innovative ideas, Nkholise is currently working to provide 1,000 3D printed breast prostheses to 1,000 women who would otherwise be unable to afford one.


Source: http://beautifulnews.news24.com/Beautiful-News/how-3d-printing-is-helping-1000-breast-cancer-survivors-20170927

3D Printing enables PhD Student to create Kidney and Prostate models

3d printed models stratasys

Nicole Wake, a PhD student at Sackler Institute of Graduate Biomedical Sciences at NYU School of Medical Sciences, has started working with Stratasys to produce patient-specific, color-coded, 3D printed kidney and prostate models using Stratasys J750 3D printer. These models are then used by physicians to enhance the treatment of several patients and guide surgeons before performing the surgeries.


Source: http://www.stratasys.com/resources/case-studies/education/nyu#_ga=2.223945054.43298708.1505905435-1750185805.1505905435

Research and Development Tax Credits to aid 3D Printing

3d printing medical devices

3D Printing has been changing the lives of many with its vast use in medical field, allowing them to print medical devices featuring complex geometries. Since the 3D Printing market will soon hit growth rate of 26.2%, a total of $2.3 billion by 2020. Firms and companies engaged in 3D Printing can use Research and Development (R & D) Tax Credit to receive aid and further enhance the era without worrying for the budget.


Source: http://www.rdtaxsavers.com/ / https://www.healthcaredive.com/news/as-use-of-3d-printing-in-healthcare-grows-hospitals-turn-to-proving-case-f/413519/

Robotic Surgery and 3D Printing comes together for first time

robotic spinal surgery

The robotic technology mixed up with 3D Printing seems like a great idea. Thanks to ROSA, the robot, the dream is finally complete. A 6-year old handicapped suffering with genetic disorder called infantile spinal amyotrophy and severe progressive scoliosis was recently treated with spinal surgery held at University Hospital of Amiens in France. 3D Printed models helped the ROSA install ilio-sarcal screws and practice the complete surgery before the child received the treatment.


Source: https://sherbrooktimes.com/amiens-a-child-operated-on-for-scoliosis-with-a-robot-a-first-in-the-world/16390

3D Bioprinted Vascular Tissue Scaffolds to enter market: 3Dynamic Systems

3d bioprinted vascular scaffolds

The 3D Printed Vascular Tissue Scaffolds were recently developed by 3Dynamic Systems, a company in Swansea University, Wales. The scaffolds can be used to treat microtia and the company has announced that the commercial market can soon see these scaffolds which can be used for surgical therapy and transplantation while also speed up the field of reconstructive medicine.


Source: http://www.bioprintingsystems.com/news.html

Formalabs submits Newer Biocompatible 3D Printing Resins

formlabs biocompatible resin

Formlabs recently introduced a biocompatible resin in desktop 3D printing called Dental SG which allows dental practitioners to create things like customized drill guides using 3D printing. Formlabs has now introduced a new dental 3D printing resin known as Dental LT Clear. It is the first long-term biocompatible resin in desktop 3D printing, available to be used for orthodontic devices.


Source: https://www.tctmagazine.com/3d-printing-news/formlabs-biocompatible-desktop-3d-printing-resin-dental/

Johnson & Johnson steps out to 3D Printing for Medicine

johnson and johnson medicine

Johnson & Johnson has gone in collaborations with HP and major 3D Printing companies like GE Healthcare in its advanced manufacturing lab which is stocked with 3D printers, robots and other advanced technology. The Johnson & Johnson 3D Printing  Center of Excellence believes 3D printing can be a boon for technology in medicine as well as the pharmaceutical, medical device and consumer uses of the technology to a mainstream or a global level.


Source: https://www.ge.com/reports/joint-venture-ge-johnson-johnson-making-3d-printed-body-parts-reality/

3D Printed Spinal Implant alleviates Nerve Pain

3d print spinal implant australia

Dr. Ralph Mobbs from Sydney Spine Clinic, New South Wales, recently performed a surgery that consisted of 3D Printed Titanium Custom Spinal Implant for a 33-year old patient named Evan Horvat from Wollongong. With the 3D Printing and Softwares- 3DMorphic and 3DMPlato, he was able to relieve the intense pain of nerve in his back and leg, due to a bulging disc and a major congenital defect that caused a joint in his lower spine to be abnormally shaped


Source: http://www.abc.net.au/news/2016-02-22/tumour-patient-gets-worlds-first-3d-printed-vertebrae/7183132

Conjoined Twins separated through 3D Printing hit the first milestone

mcdonald twins update

The craniopaqus twins who were born as conjointed twins last year in Children’s Hospital of Montefiore [CAHM], New York, underwent 20 hour surgery with the help of 3D Printing Systems. A highly specialized 3D Printed Model was created of the conjoined twins which guided the surgeons towards a successful surgery with perfect incisions. It has been 1 year now and they seem to be progressing perfectly normal over milestones of childhood.


Source: http://www.parents.com/toddlers-preschoolers/everything-kids/update-conjoined-twins-are-making-incredible-progress-just-9/

Bored of Traditional Prosthetics? Glaze Prosthetics is just here!

3d printed glaze prosthetics

Gone those days with the traditional unpleasant and colorless prosthetics. Glaze Prosthetics, a Polish based company has now introduced more choices to the owners by introducing completely customizable 3D Printed prosthetics. The clients can get various colors with choice on shape and size with high tech accessories. These prosthetics are believed to be light-weight and comfortable and fit for individual clients with a slightly modern look and useful functions.


Source: https://glazeprosthetics.com/

United States Citizen receives 3D Printed Sternum and Rib Cage

3d printed sternum rib cage

Penelop Heller, a patient of Chondrosarcoma, a rare cancer of bones and joints, underwent surgery for removal of cancer affected parts. She received Gore-Tex and Bone cement impants which caused trouble with pain and breathing. She later agreed to get a 3D Printed Sternum and Partial Rib Cage made of titanium and porous polyethylene. She is now the first patient in United States to recieve this treatment.


Source: https://www.csiro.au/en/News/News-releases/2017/NYC-patient-recieves-aussie-made-3d-printed-sternum

3D Printed Models are the best tools for Clinicians

virtual human modeling interview

Initially started as Living Heart Project by Dassault Systemes in May 2014, the project has been expanded extensively to reach out clinicians over various zones. The company is currently working on expanding the project to stimulating drug interactions with the heart, which could predict if a specific drug would have a negative, toxic effect on the heart. The company believes the 3D Printed Models will continue to amaze the medical field and become the best tools for clinicians over time.


Source: http://namforum.3ds.com/#

3D Printed Titanium Implants and Bone Grafting combined for first time

3d printed jaw implant bone graft

Researchers at the Marriston Hospital, Wales recently unveiled ADEPT [Additive-manufacture for Design-led Efficient Patient Treatment] project in surgeries to reconstruct jaws affected by cancer. The hospital claims that its technique is the first of its kind as it combines bone graft with 3D printed titanium implants. Surgeons uses a piece of fibula from patient’s leg to replace sections of jaw that have been damaged.


Source: http://www.wales.nhs.uk/sitesplus/863/news/46466

Citrene resins can revoultionize 3D Printing : Poly6

mit students citrus biomaterial

Poly6 recently developed a new biomaterial called Citrene, made from citrus rinds. Citrene resins are strong , flexible and biodegradable materials and outform other materials, offering not only safety and environmental friendliness but are also cost efficient to manufacturers. The main ingredient constitutes a natural oil making it fit for human consumption. The company is also looking to use bioprinter from Aether to explore the uses of Citrene.


Source: http://www.poly6.com/citrene/

BASF and Poetis renew agreement for 3D Printed Skin

basf poietis bioprinting

Two years ago, BASF and Poietis signed an agreement regarding the3D printing of skin for cosmetic purposes. BASF wanted to use Poietis 3D laser-assisted bioprinting technology to further develop its Mimeskin tissue. The technology works on focusing a laser on bioink, which causes droplets of the ink to fall onto a substrate seeded with cells. The use of this technique eliminates the need for testing the products on animals.


Source: https://cellink.com/basf-poietis-renew-partnership-develop-3d-bioprinted-skin-models-cosmetics-testing/

France Women receives 3D Printed Shoulder Implant after Shooting Crisis

3d printed shoulder implant

Nathalie Dufaut Danjon was shot by a man with a hunting rifle when the bullet entered her shoulder joint through the front and exited through her shoulder blade. Her shoulder's bony anatomy was destroyed, though the nerves were not affected. With the help of 3D Printing, Loose bone fragments were attached to muscle and membrane, by Dr. Brice Viard, an orthopedic surgeon at Centre Hospitalier Universitaire in Dijon, France. She has recovered greatly since then and thanks 3D Printing for the hope for new life.


Source: http://www.materialise.com/en/blog/advanced-destruction-glenoid-3d

Electronics Manufacturing to re-invent 3D Print Medicine: University of Michigan

university of michigan medicine

Researchers at the University of Michigan have discovered a new 3D printing technology which allows them to print precise doses of medication onto dosing devices such as dissolvable strips, similar to breath strips, or microneedle patches.It works by inert gas and evaporated medication travelling through a nozzle, which is pointed at a cooled surface. The medication then condenses on that surface and sticks to it in a thin crystalline film. The technique could also allow doctors and pharmacists to combine multiple medications into one easy-to-deliver dose.


Source: https://news.engin.umich.edu/2017/09/printed-meds-could-reinvent-pharmacies-drug-research/

3D Printed Human Retina Developers receive $90K by National Eye Institute

3d printed retinal model

National Eye Institute (NEI) announced in May that it would be awarding $1 million to whoever could create the best, most true-to-form lab-grown miniature retina in a petri dish. The competition was part of the 3-D Retina Organoid Challenge, which was launched by the National Institutes of Health (NIH). The winning team was later announced, which was awarded $90,000, was led by Erin Lavik, ScD, from the University of Maryland. The 3D bioprinted retinal models were designed to allow researchers to study and find new ways to prevent the development of eye conditions such as age-related macular degeneration, glaucoma, and diabetic retinopathy – as well as to enable better pharmaceutical testing.


Source: http://www.mdmag.com/medical-news/nei-awards-90k-for-proposal-for-3d-printing-human-retina

3D Printed Virus Models help understand the Influenza Epidemics

3d printed viruses students

Students at CQUniversity are working to better understand how virus mutations happen, as well as the nature of other virus-borne diseases, with the help of 3D printing. CQUniversity’s medical and engineering departments are working together to scale up several virus models to about the size of a softball and 3D print them, so that students can hold and examine them from every angle. Dr. Padraig Strappe, Senior Lecturer in Medical Laboratory Science, concluded that by 3D printing a scaled-up flu virus they could highlight the haemmagluttin, which is the part of the virus that changes from year to year.


Source: https://www.cqu.edu.au/cquninews/stories/general-category/2017/cqu-students-use-3d-printing-to-get-close-to-understanding-influenza-virus

Spinal Surgeons receives training from 3D Printed Vertebrae Models

3d printed vertebrae models

A new NTU (Nottingham University) project is focusing on 3D printed replica human vertebrae as part of pre-surgical training. The bone models are 3D printed in PLA material and a binding agent, then coated in polyester; the interior is made of polyurethane, and silicone is used to make the discs between vertebrae. Currently, the models are being created for surgeons who will be performing procedures such as laminectomies, where they may have to remove bone tissue to relieve a patient’s trapped nerves.


Source: https://www.ntu.ac.uk/about-us/news/news-articles/2017/10/lifelike-3d-printed-bones-to-help-train-spinal-surgeons

Micro Organs by 3D Printing to replace Human Clinical Trials for Drug Testing

body on a chip system organoids

Clinical trials of newer drugs are somewhat risky in humans, thanks to 3D Printing, the newer organ-on-a-chip have been introduced that can cut off the risk. This newer technology is used to produce micro organs called organoids, especially liver, heart and lung which can then be used to test the drugs before use in humans. The technology is further being improved at Wake Institute for Regenerative Medicine with aid from Wake Forest Baptist Medical Center.


Source: https://www.sciencedaily.com/releases/2017/10/171005121056.htm

3D Printed Medical Marijuana Inhaler by Syqe

3D Printed Medical Marijuana Inhaler by Syqe

Syqe Medical, an Israeli drug delivery company has introduced a 3D Printed Medical Marijuana Inhaler which can deliver metered doses of cannabis or weed, thereby providing a controlled treatment. The inhaler will be free of smoke or other carcinogenic materials, and is expected to be distributed by Teva Pharmaceuticals, once the FDA approval is gained next year.

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Recreating Microvasculature with 3D Printing

Coronary Microvasculature 300x300 2

One roadblock to 3D printing complete, functional organs lies in our inability to ensure the engineered tissue will be well nourished with an accessible blood supply.  Presently we have seen attempts at recreating arteries and veins, but successfully ensuring blood flow deep into tissue to the level of the capillary beds has proven elusive. A group of bioengineers and clinicians have pioneered a technique allowing them to print a fibrin patch containing organized endothelial cells, the cellular linining of blood vessels. Not only did the printed patch enhance blood vessel formation, but the engineered vascular tissue actually integrated with the host's own vasculature, improving tissue perfusion of damaged tissues. This research provides a novel technique that may permit printing of larger blocks of tissue and even organs.

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3D Printed Stents for a Perfect Fit in Every Heart

Vascular stent crop

Two professors at Northwestern’s McCormick School of Engineering, Guillermo Ameer and Cheng Sun, have developed a method of 3D printing patient-specific vascular stents that are both flexible and biodegradable. These 3D printed stents can be pre-loaded with drugs that are released at site of implant, shortening the healing process in the walls of blood vessels. Meanwhile the unique polymer material allows the stent to exercise its mechanical function during the vessel’s initial dilation but slowly dissolve as the re-opened blood vessel recovers.

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Roller Coaster Relief from Kidney Stones? 3D Printing Provides Proof-of-Concept

3D Printing proves Roller Coaster Rides can make Kidney Stones pass

Anecdotal evidence had suggested that high-impact activities, such as roller coaster riding or bungee jumping, could result in spontaneous passage of kidney stones, however 3D printing has now been used to validate the efficacy of a trip to Magic Mountain next time you suffer from kidney stones.  A study was conducted at Michigan State University College of Osteopathic Medicine where Dr. David D. Wartinger performed research on whether roller coaster rides can actually facilitate kidney stone passage. A 3D replica of a patient’s kidney was printed in clear silicone material and then was monitored with ureteroscopy during a roller coaster ride. The results verified that roller coaster rides can assist kidney stone passage.

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MatterHackers announces winners of WithinReach Contest

Winners of WithinReach by MatterHackers announced

The contest WithinReach, started on July 11th and ended on Sepember 6th was held by MatterHackers was held by MatterHackers inviting designers of all ages to participate in the event and create a 3D Printable tool to assist individuals with limited use of their hands. The event saw 203 entries out of which 6 winners were selected. The grand prize went to two students, Nima Yahyaabady (grade 7) and Aidan Mansell (grade 9) for NailIt.

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NASA, ASME and Future Engineers call for Mars Medical Challenge

 NASA ASME and Future Engineers call for Mars Medical Challenge

The collaborative venture of NASA, American Society of Mechanical Engineering (ASME) and Future Engineers, an online education platform, has led to some 3d Printing Challenges recently, and now they have come up with the Mars Medical Challenge. Aiming directly towards future Mars mission, this challenge asks participants to create a digital 3D model of a medical or dental item that an astronaut could use on a three-year mission to Mars.

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4WEB publicizes First Surgeries performed with Posterior Spine Truss System

4WEB publicizes First Surgeries performed with Posterior Spine Truss System

The Texas-Based company, 4WEB Medical earlier received the FDA clearance for the four implant systems using patented truss technology and now, they have announced the first surgeries performed using Curved Posterior Spine Truss System (PSTS) for TLIF procedures in U.S. The key feature noted by the orthopedics using this implant is the truss structure that that strengthens and reinforces the capabilities of orthopedic implants.

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Plum Alley Investment grants funds to Epibone

 Plum Alley Investment grants funds to Epibone

Dr. Nina Tandon, CEO of Epibne has started bioprinting human bones using CT scan and 3D model of it, which is then CNC milled with animal bone, following which, fat cells from patient are integrated with CNC milled animal bone. Plum Alley Investments, a private membership started by Deborah Jackson and Andrea Turner Moffit to support promising female entrepreneurs and gender-diverse teams, has announced funds of $560,000 to Epibone to support this 3D Printing initiative which will reduce the need for multiple surgeries.

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Osteopore International acquires 2016’s Entrepreneurial Company of Year Award

Osteopore International acquires 2016s Entrepreneurial Company of Year Award

This year’s 3D Scaffolds Entrepreneurial Company of the Year Award in the Transformational Healthcare category have been grabbed by Singapore-based company at the Frost & Sullivan Singapore Excellence Awards. Osteopore International for their innovation in 3D Printed Scaffolding that deals with healing of tissue within the human body as well as regeneration. Set up in 1999, Osteopore has been pioneering methods of 3D Printing to provide range of innovations as well as customer satisfaction.

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Xplorer 3D provides 3D Printed Prosthetic to Pakistani Kid

Xplorer 3D provides 3D Printed Prosthetic to Pakistani Kid

Shayaan, a 9-year old from Pakistan was born with Dysmelia, a rare disorder in which limbs do not form properly and hence had no arms. Her mother, Fadia Haroon reached out to Xplorer 3D, first 3D printer manufacturer from Pakistan and the CEO of the company, Tayyab Alam prepared a custom 3D Printed Prosthetic Device for him featuring custom attachments that are lightweight and adjustable and helps with tools such as pen, comb, touch devices, etc.

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HyperElastic Bone ready for the Breakthroughs

HyperElastic Bone ready for the Breakthroughs

Researchers team led by Ramille Shah at Northwestern University, Illinois, have made progress towards a new type of bone called as the HyperElastic Bone which will be a breakthrough in modern medicine. Using bioactive hydroxyapatite, different biomaterials and EnvisionTEC 3D-Bioplotter System for 3D Printing, this new bone will provide extreme benefits to surgeons.

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