drvarun sqMedical 3D Printing & Bioprinting

Dr Varun Tyagi is a medical doctor who practices in India and writes about remarkable and historical landmarks throughout the medical world.  Dr Varun believes that 3D printing can help democratize medical care, making medical devices affordable and available to everyone on the planet.

Collaboration Between 3D Systems and Stryker for Enhancing Surgical Planning

 Collaboration Between 3D Systems and Stryker for Enhancing Surgical Planning

3D Systems and Stryker announced their exclusive distribution partnership for anatomical craniomaxillofacial and Virtual Surgical Planning (VSP) service. The agreement is specific to US, Canada, Europe, and Australia, will begin on February 1st, 2018. The partnership will help surgeons in developing customized surgical plans ahead of complex operations.

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Identities of Dead Victims on US-Mexico Border Reconstructed Using 3D Printing

 Identities of Dead Victims on US Mexico Border Reconstructed Using 3D Printing

Migrants trying to cross US-Mexico border are often apprehended and lose their live during the effort, and over 1000 unidentified in Pima Country, Arizona, were recently found. However, using the 3D Printing Technology by FARO, a 3D tech company, a group of students led by Joe Mullins from New York Academy of Art, have been working to reconstruct skulls of 8 such men. Once the reconstructions are complete, they are photographed and entered into National Missing and Unidentified Persons System (NamUS).

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5-Year Old Gifts Hands to These in Need Using 3D Printing

 5 Year Old Gifts Hands to These in Need Using 3D Printing

Cameron Haight, a 5-year old now, was born with Amniotic Band Syndrome, which caused his fingers and toes to be deformed and few amputated. Receiving her own 3D Printed Hand, she and her mother began 3D Printing e-NABLE hands for other children using the first design made by Cameron called Tool 5000. They have set up an NPO called Different Heroes to raise money for these 3D printed hands for children around globe.

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Sebaceous Glands Unveiled by BASF & CTIBiotech for Skin Care Industry

 Sebaceous Glands Unveiled by BASF CTIBiotech for Skin Care Industry

BASF and CTIBiotech came together at the recent NYSCC Cosmetic Congress where they formed a collaboration to work towards 3D Bioprinting. Now, they have announced the technology for the bioprinting of tissue to create sebaceous glands which is expected to be a boon for Skin Care Industry. The research resulted in Ex-vivo production of physiological sebum and Regulation of sebum production with active ingredients.

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Researchers Progress Towards Building Hybrid Materials for 3D Printed Implants

Researchers Progress Towards Building Hybrid Materials for 3D Printed Implants

A team of researchers from TU Delft have developed hybrid materials which can be used to 3D Print Hip Implants with enhanced bone growth and increased life-span. The new implant will combine a conventional meta-biomaterial with an auxetic one, a complex stretching property. These 3D Printed Hybrid Implants are expected to have greater longevity and fix better than current hip implants.

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3D Printing Helps Stroke Victim Return to Swimming

3D Printing helps Stroke Victim return to Swimming

Pedro, 16-year old, suffered stroke in 2012 which left him with his right hand affected by spasticity and lose fine movement. A team collaborated with Polytechnic University of Catalonia (UPC) and created a custom orthotic hand swimming fin for Pedro in less than a month using water soluble PVA material and Sigma 3D printer.

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Researchers Use 3D Printing & Cryogenics to Develop Replicas for Tissue-Regeneration

Researchers Use 3D Printing Cryogenics to Develop Biological Replicas for Tissue Regeneration

Researchers from Imperial College London (ICL) have developed new 3D Printing Technique to create biological replicas for tissue regeneration. In collaboration with Kings College London, they experimented with 3D Printing and Cryogenics using solid Carbon Dioxide (dry ice) to quickly cool down hydrogel ink and Ultimaker 3D Printer. Once the ink softens, it forms a gel as soft as human tissue, which was then seeded with Dermal Fibroblasts with success.

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Surgeons Develop Acrylic-Based 3D Printed Mask for Facial Transplant Donors

Surgeons Develop Acrylic Based 3D Printed Mask for Facial Transplant Donors

A team of 3D Printing experts at New York University (NYU) have started creating 3D Printed Masks for Facial Transplants Donors using accurate 3D Printing and Acrylic material. Since it is a tough decision to give up the face of deceased by family members, this 3D Printed Mask will encourage more people to agree to donate the faces of their dying family members for transplant purposes. Using Handheld Scanner to scan donor’s face, and then sending files to large 3D Printer, the final product is made using acrylic-based photopolymer.

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eNABLE Helps Florida Man Get Back to Life With 3D Printed Hands

eNABLE helps Florida Man get back to life with 3D Printed Hands

Francisco Piedra, 61-year old man from Florida, was diagnosed with severe aortic stenosis in 2016, for which he was given drug Heparin. The drug made situation worse and led to clots, forcing surgeons to amputate his hands and legs below knees, for which he approached Hanger Clinics from where he received Legs, but not Hands since they were above $100,000. Ultimately, eNABLE came to help and through Richard Brown, he received 3D Printed Prosthetic hand which took 20 hours each to 3D Print.

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Cellink Partners With CTI Biotech to 3D Print Tumors for Cancer Treatment

 Cellink parners with CTI Biotech to 3D Print Tumors for Cancer Treatment

Cellink, a Swedish 3D Printing Company founded by Erik Gatenholm and Hector Martinez Avila, has announced their partnership with CTI Biotech, a French company based in Lyon, to fabricate tumors that can be used for pharmaceuticals testing. The ability to mix their own inks with cells from patients’ cancers will allow them to produce tumors that can be subjected to intense research without endangering human lives and simultaneously remove animal testing.

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3D Printed Lens Provides Treatment for Seizures Due to Extreme Light

 3D Printed Lens provides Treatment for Seizures due to Extreme Light

Logan Williams, a student at the University of Canterbury, has developed a 3D Printed Polarized Lens called the Polar Optics that help fight against Epileptic Seizures caused by Photosensitivity. The lens combat the effects of flashing lights through refraction of light entering the wearer’s eyes and therefore reducing the intensity of light to reduce the damage done.

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Superhero Prosthetics Customized Specially for Children of Colombia

 Superhero Prosthetics customized specially for Children of Colombia

A Colombian company called Fabrilab founded by engineer Christian Silva in 2015 has started manufacturing Unique Prostheses for children amputees who cannot afford them. These personalized prosthetics mimic the attributes of their favorite superheroes and cost around $250-$500 each and some functionality to boot, with an ability to grasp ordinary objects.

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3D Printing in the Field of Occupational Therapy

 3D Printing in the field of Occupational Therapy

At University of Indianapolis, Dr. Erin Peterson, Assistant Professor of Occupational Therapy is working on determining the best use of 3D Printing technology in field of Occupational Therapy Education for both master’s and doctoral students. After receiving the MakerGear M3 desktop 3D Printer and Scanner, they started 3D Printing innovative designs for assistive devices and custom anatomical models, as well as using Customized 3D Printed Pill Boxes to improve daily medication routines.

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Bioengineering Students Explore the World of 3D Printing

 Bioengineering Students explores the world of 3D Printing

Victoria Sear, a graduate student from University of Michigan- Dearborn was introduced with 3D Printing Technology during an internship with SME and variety of things 3D Printing could offer. As a Bioengineering student, she was fascinated to learn about 3D Printed Prosthetics as replacement limbs, 3D Printed Heart models that were used to help prepare medical teams for surgical interventions, and a wide variety of medical devices that could be custom fabricated for patient-specific needs.

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MSF Hospital Utilizes 3D Printed Prosthetics in Reconstructive Surgeries

 MSF Hospital utilizes 3D Printed Prosthetics in Reconstructive Surgeries

Médecins Sans Frontières (MSF), also known in English as Doctors Without Borders, a foundation that reached out to 3D Printing Technology for its hospital to treat war-wounded Iraqis without access to health care. As the reach extended, the MSF Foundation started providing 3D Printed Prosthetics to Syria, Palestine and Libya through the hospital’s reconstructive surgery program. These prosthetics are faster and cheaper to produce using desktop Ultimaker 3D Printer.

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The Possibilities Are Endless With 3D Printing: Duke University

 The Possibilities are Endless with 3D Printing Duke University

Duke University School of Medicine is making every possible use of 3D Printing they can in their medical efforts. From creating a 3D Printed Model of Hip at campus Co-Lab Studio through MRI and CT scans to aid in surgery for Chronic Limp in young woman; to enhancing Transcatheter Aortic Valve Replacement, a procedure for Aortic valve stenosis via a 3D Printed Model of flexible anatomy of aorta by Dr. Alice Wang at Duke University.

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3D Printed Blood Brain Barrier to Eliminate Need of Animal Testing

 3D Printed Blood Brain Barrier to eliminate need of Animal Testing

Blood Brain Barrier (BBB) is a semi-permeable that protects brain from direct contact with damaging entities in body. Until now, animals have been used to test drugs that cross BBB, but now researchers are capable of reproducing the microcapillaries of neurovascular system on 1:1 scale using 3D Printing technology. Carried out by Gianni Ciofani, Associate Professor at Polytechnic University of Torino, the mimicked BBB is important for developing pharmaceuticals that can cross boundary as there currently exist drug compounds that demonstrate great potential for addressing brain diseases such as Alzheimer’s, Parkinson’s and ALS.

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New Bioprinting Ink Will Open the World for Scaffolds

New Bioprinting Ink will open the world for Scaffolds

A group of researchers from Japan’s Osaka University have developed a new bioprinting ink using a method based on hydrogelation mediated by horseradish peroxidase, an enzyme that can create cross-links between phenyl groups of an added polymer in the presence of the oxidant hydrogen peroxide. This bioprinting ink will be better substitute of Sodium Alginate as it will allow 3D Printing of more variety of scaffolds.

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3D Printed Bones Especially for Ethnically Chinese People by ITRI

 3D Printed Bones especially for Ethnically Chinese People by ITRI

The Industrial Technology Research Institute (ITRI) of Taiwan has developed bone material specially designed for ethnic Chinese people using 3D printing to combine metal and ceramic composite materials with bionic bone structures, and is expected to come in 2018. The ITRI-developed 3D printed bone material is lightweight, hydrophilic, and fuses easily with existing bone. It’s porous and hollow and can be used to regenerate natural bone, plus it can be easily customized for personalized treatment.

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Functional Kidney With Vasculature Almost Close for Wyss Researchers

 Functional Kidney With Vasculature Almost Close for Wyss Researchers

A team of researchers in tissue engineering, 3D biofabrication, biomaterials design and stem cell differentiation at Harvard’s Wyss Institute is working on 3D Printing a Functioning Kidney Subunit with current work to build branched vascular network unique to each organ. Using advanced 3D Bioprinting from Wyss Institute, Dr. Jennifer Lewis’s organ-on-chips are ready, using special polymer inks for creation of structures made up of human cells, complete with vasculatures and extracellular matrices.

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FDA Guidance and R&D Tax Credits for 3D Printing Companies

 FDA Guidance and RD Tax Credits for 3D Printing Companies

Before 3D Printing Medical Devices can be used for clinical applications, they must first get approval from FDA. On December 4, 2017, the FDA issued a guidance to help speed up the approval process for companies seeking the approval. Additionally, there were Research and Development tax credits that a company can seek to offset 4-7% of the cost associated with testing, process improvement, and production. To receive the research and development benefits, the company must meet the four eligibility criteria set up.

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Physician Drives Long Way to Deliver 3D Printed Prosthetics to Children for Charity

 Physician drives long way to deliver 3D Printed Prosthetics to Children for Charity

A 29-year old, Dr. Lars Brouwers is a physician from Tilburg, Netherlands, who is on a mission to deliver 3D Printed Prosthetic Hands to children who faced war violence in Sierra Leone. For the charity, he is also delivering a desktop 3D Printer, Ultimaker 3 with cost of $3,000 but donated for free by Ultimaker. Using a 1995 Saab for three week long drive to Sierra Leone, they will supporting the charitable international Global Minimum organization, and its Innovate Salone program for school children, with their 3D printed prosthetic hands.

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These 3D Printed Spermbots Are the Ultimate Warriors in Battle Against Cervical Cancer

 These 3D Printed Spermbots are the Ultimate Warriors in Battle Against Cervical Cancer

Researchers from Institute for Integrative Nanosciences (IIN) at IFW Dresden in are working to develop a Biohybrid Sperm Microbot, which could be used in the future to deliver anti-cancer drugs like doxorubicin hydrochloride to cancerous tumors in women’s reproductive tracts, and help in cancer like Cervical Cancer. The tests had already been successful, the team is just working to make the invisible drug delivery system a bit more accessible to hospitals and simultaneously monitor the spermbot’s movement inside the body in real time.

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China Develop Better Method of 3D Printing Patient-Specific Liver Models

 Chinese Researchers develop Cheaper Precise Method of 3D Printing Patient Specific Liver Models

A team of researchers led by Professor Cheng Shujie from Affiliated Hospital of Hebei University, China are unveiling precise 3D Printed Liver Models which have been 3D Printed using Stereolithography for lower costs & precision and can be used for aiding in surgeries. Using two high speed LCD-SLA 3D printers, the team was able to create detailed, life-sized liver model for approximately $80-$90.

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CADskills Titanium 3D Printed Implants Is the Solution to Bone Atrophy

 CADskills Titanium 3D Printed Implants is the solution to Bone Atrophy

CADskills, a medical device startup from Belgium uses 3D Printing Technology to produce patient-specific implants for craniomaxillofacial (CMF) and neurosurgery patients, including its innovative AMSJI, a new generation of subperiosteal implant for extreme maxillary atrophy. To counter bone atrophy, AMSJI eliminates the bone grafting process and its months of recovery time and the surgery takes around 1 hour. These Titanium implants are 3D Printed using Mimics Innovation Suite (MIS) from Materialise.

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Researchers Develop 3D Printed Liver Model for Accurate Drug Toxicity Testing

 Researchers develop 3D Printed Liver Model for Highly Accurate Drug Toxicity Testing System

An international research team collaborated to 3D Print Simple Liver Model using bioprinted tissue to develop a more accurate drug toxicity testing system. The new advancement can construct vascularized tissue, which is then able to mimic drug administration in vivo in 3D bioprinted liver tissue. This new model will allow scientists to observe the in vivo effects of drug absorption without having to actually set up a real in vivo study.

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3D Printing the “Fingers” Made for Music

 3D Printing the Fingers made for Music

The research team, Gil Weinberg, Minoru Shinohara, Chris Fink, and Levent Degertekin, have been working with amputee Jason Barnes, a musician, to develop a prosthetic hand based on Open Bionics’ open source design that can move each finger individually. Instead of electromyogram (EMG), they used Ultrasound to detect muscle movements which allowed them to create prosthetic that could move each finger individually.

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A 3D Printing Accident That Led to Super Tissue Paper With Biological Properties

 A 3D Printing Accident that led to Super Tissue Paper with Biological Properties

During the recent project, where researchers from Northwestern University were implanting a 3D Printed Working Ovary in mouse, Adam Jakus, a postdoctoral fellow in Professor Ramille Shah’s lab, was preparing 3D printing ink made from ovarian cells which he accidentally spilled, ultimately leading to discovery of “Tissue Paper”. This “Tissue Paper” can be used to restore normal hormone function to young cancer patients and restored fertility to women. Research team is planning to use it to repair organs and bioactive Band-Aid that would facilitate the healing of a wound.

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Protosthetics & C2renew Partner to Create 3D Printing Filament for Prosthetic Sockets

 Protosthetics and c2renew Partner to Create 3D Printing Filament for Definitive Prosthetic Sockets

Protosthetics and c2renew, both North Dakota based companies have announced their partnership and work together to 3D Print definitive Prosthetic Sockets with enhanced strength and quality. Developing a 3D Printing Filament, for the Sockets, as well for 3D Printing Orthotics, the two teams came together in creating a combination of industrial polymers and unique strengthening fibers.

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Researchers From University of Oxford Develop Self-Sustaining Cells Using 3D Bioprinting

 Researchers from University of Oxford develop Self Sustaining Cells using 3D Bioprinting

A group of researchers at the University of Oxford have developed a new method of bioprinting that involves self-contained, self-supporting cells using a droplet-based 3D bioprinter. Researchers were able to successfully 3D printed human embryonic kidney (HEK) cells and ovine mesenchymal stem cells (oMSCs) at a high droplet resolution of one nL. The ability to 3D print with adult stem cells is believed to have a greater impact on regenerative medicine globally.

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Camber Spine and Renovis Tech Receives FDA (510)k Clearance for Spinal Implants

 Camber Spine and Renovis Surgical Technologies receive FDA 510k Clearance for their Spinal Implants

Two companies recently announced that they have received (510)k clearance from the US Food and Drug Administration (FDA) for 3D printed titanium spinal implants. While Camber Spine Technologies from Pennsylvania received FDA clearance for its SPIRA Open Matrix ALIF device, an interbody fusion implant; the other one was Renovis Surgical Technologies from California for its posterior lumbar Tesera porous titanium interbody fusion systems.

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ENEA 3D Printed Walking Stick From Shiro Studio Is the Modern Powerful Tool

 ENEA 3D Printed Walking Stick from Shiro Studio is the Modern Powerful Tool

The ENEA walking stick was designed and 3D Printed by Andrea Morgante, founder of Shiro Studio, a London-based architectural design firm, in 2009. The ENEA stick is developed from a porous internal structure that mimics trabecular bone tissue, and this porous internal structure allows the walking stick to be lightweight yet sturdy, as does its 3D printed construction. The walking stick is stylish yet strong, and also features a twiglike protrusion near one end so that it can be hooked onto desks, tables or counters.

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Indian Students Turn to Fracktal Works to 3D Print Robotic Prosthetic Arm

 Indian Students turn to Fracktal Works to 3D Print Robotic Prosthetic Arm in Final College Project

Four students from MVJ College of Engineering, Bangalore had planned to 3D Print a Robotic Prosthetic Arm for their Final project in the college. But things were not easy, for which they turned to Fracktal Works, a Bangalore-based 3D Printing Company which helped the students to optimize their design for 3D printing and add a power source with 12 Gesture codes into the hand. The final device was 3D printed in PLA, in 40 parts, which was then assembled.

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IdiPAZ Researchers in Spain Roll 3D Printed Corneas to Tackle Huge Demand of Donors

 IdiPAZ Researchers in Spain pave way for 3D Printed Corneas to tackle Huge Demand of Donors

Researchers at Biomedical Research Institute of La Paz Hospital (IdiPAZ) in Spain are working to 3D print cornea substitutes, using a patient’s own stem cells and thereby reduce the huge global demand of over 10 million people to donate corneas. The project called ‘Cornal stroma fabrication’ will include use of steam cells from patients to be used for 3D printing the custom corneas and using tissue engineering to regenerate different layers of the cornea for Corneal Transplant.

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Utah’s BYU Unveils First 3D Printed Microfluidic Device Working Under 100 Micrometers

 Researchers from Utahs BYU unveil First 3D Printed Microfluidic Device capable of working below 100 Micrometers

Researchers from Brigham Young University (BYU) in Utah have developed the first working microfluidic device that’s small enough to be effective at a scale less than 100 micrometers using 3D Printing Technology. The key focus involved building their own 3D printer to print at a much higher resolution and using a new, specifically designed, low-cost, custom resin. Also, the digital light processing stereolithography (DLP-SLA) helped them seek low-cost approach for project.

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3D Printed Cancer Cells May Help Researchers Develop Effective Treatment for Breast Cancer

 3D Printed Cancer Cells may help Researchers develop Effective Treatment for Breast Cancer

A team of scientists in New Zealand are 3D Printing Tumor cells using real cells and then using them to develop new treatment plans for Breast Cancer. Dr. Elisabeth Phillips and Khoon Lim, also of the University of Otago, came up with the 3D printing idea and obtained funding to research breast cancer through bioprinted tumors. The team believes it is first of its kind in New Zealand following 3D printing of brain tumor cells in Scotland.

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Researchers Develop Diagnostic Tool Better Than ELISA Using Inkjet 3D Printing

 Researchers develop Diagnostic Tool better than ELISA using Inkjet 3D Printing

Researchers at Duke University have used 3D inkjet printing to create a diagnostic tool that has the potential to be better than ELISA, the diagnostic test for a variety of diseases like HIV AIDS. The 3D printed biomedical tool, called D4 Assay, can be used in point-of-care settings to screen patients, has high accuracy and can reduce the time of diagnosing from days to 15 minutes. It is a self-contained test in the vein of a lab-on-a-chip that can detect low levels of antigens from a single drop of blood. The scientists used inkjet technology to print an array of antibodies onto a glass slide with a nonstick polymer coating.

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Researchers in India Develop 3D Printing Software to Create Prosthetic Ear in One Week

 Researchers in India develop 3D Printing Software to create Prosthetic Ear in just one week

A team from the College of Engineering, Pune (CoEP) in India has developed unique software, which helped them make a 3D printed ear in just one week for 32-year-old patient from Kondhwa. The newly developed software is called Osto3D, and reduces the fabrication time greatly. The successful auricular prosthesis surgery was performed last month, when doctors from the Armed Forces Medical College (AFMC) attached the artificial ear.

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Aether and UniSA to Use 3D Bioprinting for Contraception Under Gates Foundation Project

 Aether and UniSA to use 3D Bioprinting for Contraception under Gates Foundation Project

San Francisco-based Aether has announced a project collaboration with UniSA to pursue a 3D bioprinting research breakthrough in contraception using their own Aether 1 3D Bioprinter and the project is being funded by a grant from the Bill and Melinda Gates Foundation. The goal of the project is to develop an in vitro oviduct model, which will replicate the “spermatozoa capacitation process” in order to screen natural products and novel drugs which will target this process in the oviduct, resulting in a brand new contraceptive paradigm.

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Korean Surgeons Develop Guides for Removing Cancer & Rebuilding Jawbone at Same Time

 South Korean Surgeons develop 3D Printed Guides for removing Cancer Rebuilding Jawbone at same time

A team of researchers at Samsung Medical Center announced that they have a successful method for using 3D printing to rebuild the jawbones of oral cancer patients. Led by Professor Baek Chung-hwan of the department of otolaryngology, the medical team created a 3D printed surgical guide that allows them to rebuild areas of the jaw as well as eliminating areas that are ridden with cancer. The team was able to perform surgery and reconstruction all at once, using the new bone made from the patient’s leg bone, fibula.

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